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MT103
MT477
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MT103
family of therapeutic
compounds
Treatment for
Non-small Cell Lung Cancer
Updated: August 1,
2007
Product Family
The MT103 family
of therapeutic compounds was screened from tens of thousand of designed
candidates with an optimal activity profile against non-small cell lung
cancer, using Medisyn’s Forward Engineering™ in silico techniques.
MT103 predictions for activity and specificity have been validated in
vitro with the National Cancer Institute (NCI) 3-cell and 60-cell line
testing. In addition to identifying active chemical analogs, Medisyn has
designed “property analogs” as backup lead candidates – these are
chemically diverse structures possessing the same therapeutic properties
as MT103. Drug-like MT103 and its analogs show remarkable promise and
potential as candidates for pre-clinical and clinical evaluation.
At-a-glance
| MOLECULE TYPE:
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Small Molecule
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| ACTIVTY AGAINST:
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- Non Small Cell Lung
- Breast
- Renal
- Prostate
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| MECHANISM OF ACTION:
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- Protein Kinase-C Inhibition
- Induction of Apoptosis Via PKC
Pathway
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| TOXICITY: |
No observable toxicity in limited in vivo
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| STAGE OF DEVELOPMENT:
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Mid Pre-Clinical with completed Animal Xenograft
Study
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| DEAL TYPE:
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Worldwide License
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