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MT103 family of therapeutic compounds
Treatment for Non-small Cell Lung Cancer
Updated: August 1, 2007
 

Product Family

The MT103 family of therapeutic compounds was screened from tens of thousand of designed candidates with an optimal activity profile against non-small cell lung cancer, using Medisyn’s Forward Engineering™ in silico techniques.  MT103 predictions for activity and specificity have been validated in vitro with the National Cancer Institute (NCI) 3-cell and 60-cell line testing. In addition to identifying active chemical analogs, Medisyn has designed “property analogs” as backup lead candidates – these are chemically diverse structures possessing the same therapeutic properties as MT103. Drug-like MT103 and its analogs show remarkable promise and potential as candidates for pre-clinical and clinical evaluation. 

At-a-glance

MOLECULE TYPE:
Small Molecule
 
ACTIVTY AGAINST:  
  • Non Small Cell Lung
  • Breast
  • Renal
  • Prostate
MECHANISM OF ACTION:  
  • Protein Kinase-C Inhibition
  • Induction of Apoptosis Via PKC Pathway
     
TOXICITY:
No observable toxicity in limited in vivo
 
STAGE OF DEVELOPMENT:
Mid Pre-Clinical with completed Animal Xenograft
Study
 
DEAL TYPE:
Worldwide License
 
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